Prepare the Crust Mixture. In a small bowl, combine the grated Parmesan cheese, panko breadcrumbs, garlic powder, paprika, salt, black pepper, olive oil, and lemon zest. Mix until well combined.
Prep the Salmon. Preheat your oven to 400°F. Line a baking sheet with parchment paper or lightly grease it. Place the salmon fillets on the baking sheet, skin-side down if the skin is on.
Apply the Crust. Press the Parmesan mixture onto the top of each salmon fillet, ensuring an even layer. Gently press down to help the crust adhere to the salmon.
Bake the Salmon. Bake in the preheated oven for 12-15 minutes, or until the salmon is cooked through and the crust is golden brown. The internal temperature of the salmon should reach 145°F.
Serve. Transfer the salmon to a serving platter and garnish with fresh parsley if desired. Serve with lemon wedges for squeezing over the top.